$32.00
At BasePeptides.us, we provide rigorous academic research materials designed for specialized laboratory investigations. Adipotide (also designated as pro-apoptotic peptide PPI-1458) is a synthetic peptidomimetic developed to study targeted vascular disruption within adipose tissue. Composed of a homing domain linked to a pro-apoptotic sequence, this molecule is engineered to bind specific cell-surface receptors on white adipose tissue vasculature, initiating targeted apoptosis in endothelial cells that feed fat depots.
Molecular Weight: Approximately 1,600 to 1,800 g/mol (dependent on salt form)
Purity: $\ge$98% (Verified via HPLC and Mass Spectrometry)
Form: Lyophilized reference powder
Explore high-purity Adipotide at Basepeptides.us, a specialized pro-apoptotic peptidomimetic engineered for advanced vascular disruption and metabolic research applications.
CAS Number: 1152817-09-4 (Peptide sequence registry)
Storage: Store at -20°C, desiccated and protected from light
In preclinical models, researchers utilize the adipotide peptide to investigate the complex signaling mechanisms involved in angiogenesis, endothelial cell survival, and vascular targeted apoptosis. The compound’s structural design relies on two functional motifs: a binding domain that targets prohibitin and ANXA2 on the surface of white adipose tissue endothelial cells, and a pro-apoptotic domain (such as the D(KLAKLAK)2 sequence) that disrupts mitochondrial membranes once internalized.
Academic laboratories evaluate several core areas during in vitro and animal model assays:
Vascular Disruption Kinetics: Assessing selective reduction of blood supply to metabolically active white adipose tissue depots.
Apoptotic Signaling Cascades: Measuring caspase activation and mitochondrial membrane depolarization in targeted endothelial cell lines.
Metabolic Parameter Shifts: Analyzing downstream physiological responses in preclinical metabolic dysfunction models.
When setting up experimental protocols, investigators often procure a standardized adipotide 10mg vial configuration, which offers precise reconstitution volumes for in vitro cellular assays and preliminary dose-response curves.
For institutional bio-analytical laboratories, identifying a reliable source offering adipotide for sale requires rigorous verification of third-party analytical testing, including high-performance liquid chromatography and mass spectrometry reports confirming sequence integrity. Similarly, when exploring specialized registries listing an adipotide ftpp for sale option (referencing its targeted pro-apoptotic peptide structure), researchers must ensure complete transparency regarding batch purity. Basepeptides.us maintains strict quality control protocols, supplying research-grade materials exclusively for scientific and laboratory experimentation.
This product is sold strictly for laboratory research use only. Not for human consumption. By purchasing, you acknowledge that you are at least 18 years of age and that this product will be used exclusively for legitimate research purposes. Peptides require reconstitution, instructions are not provided, nor are directions on dosing and usage. Products are intended strictly for research purposes by skilled professionals.
