Glutathione

$199.00

Cellular Antioxidant Dynamics: Glutathione

At BasePeptides.us, we supply premium research-grade biochemicals for advanced laboratory investigations. is a critical endogenous tripeptide antioxidant synthesized intracellularly from three constituent amino acids: L-glutamate, L-cysteine, and glycine. As a primary intracellular redox buffer, it plays a central role in maintaining cellular homeostasis, neutralizing reactive oxygen species (ROS), and supporting enzymatic detoxification pathways across biological models.

Technical & Product Specifications

  • Molecular Weight: 307.32 g/mol

  • Chemical Structure: $\gamma$-glutamyl-cysteinyl-glycine (with an active thiol group on the cysteine residue)

  • Purity: $\ge$99% (HPLC Verified)

  • Form: Lyophilized reference powder / High-purity crystalline standard

  • CAS Number: 70-18-8

  • Storage: Store at -20°C, protected from moisture and light

Biochemical Mechanisms & Cellular Assays

In biological systems, the ratio of reduced to oxidized glutathione serves as a primary marker of cellular oxidative stress. The active thiol group allows the molecule to act as an electron donor, reducing peroxides and free radicals while converting into its disulfide-linked oxidized form ($\text{GSSG}$).

In vitro laboratories and biomedical research facilities analyze these pathways to evaluate cellular protection mechanisms:

  • Redox Regulation: Measures intracellular enzyme kinetics involving glutathione peroxidase and glutathione reductase.

  • Xenobiotic Detoxification: Assesses conjugation reactions mediated by glutathione S-transferase (GST) in cellular exposure assays.

  • Mitochondrial Bioenergetics: Investigates oxidative phosphorylation efficiency and membrane integrity under oxidative challenge models.

Formulation Delivery & Sourcing Considerations

While standard oral formulations face rapid enzymatic degradation in the gastrointestinal tract, researchers exploring alternative administration and cellular delivery models frequently study advanced encapsulation techniques, such as liposomal , to evaluate enhanced cellular uptake and bioavailability parameters.

In clinical or systemic medical applications, practitioners evaluate therapeutic injections for targeted parenteral administration. Conversely, consumer markets often examine an oral glutathione supplement or commercial preparations like cymbiotika glutathione for systemic wellness routines. For independent bio-analytical laboratories, acquiring standardized research materials requires verified third-party purity assays and strict quality control protocols to ensure reproducible experimental data. Basepeptides.us maintains comprehensive analytical documentation for all catalog items to support advanced cellular research.

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This product is sold strictly for laboratory research use only. Not for human consumption. By purchasing, you acknowledge that you are at least 18 years of age and that this product will be used exclusively for legitimate research purposes. Peptides require reconstitution, instructions are not provided, nor are directions on dosing and usage. Products are intended strictly for research purposes by skilled professionals.