$110.00
At BasePeptides.us, we provide high-purity research compounds for advanced laboratory investigations. Aicar (5-Aminoimidazole-4-carboxamide ribonucleoside) is a cell-permeable analog of adenosine monophosphate (AMP) that functions as a potent, allosteric activator of AMP-activated protein kinase (AMPK). In cellular biology, AMPK serves as a master regulator of energy homeostasis, responding to shifts in cellular energy status by modulating downstream metabolic pathways.
Molecular Weight: 258.23 g/mol
CAS Number: 2627-69-2
Purity: $\ge$98% (Verified via HPLC and Mass Spectrometry)
Form: Lyophilized reference powder
Storage: Store at -20°C, desiccated and protected from light
Once transported across the cell membrane via adenosine transporters, the compound is phosphorylated intracellularly to form ZMP (5-aminoimidazole-4-carboxamide ribonucleotide), which mimics endogenous AMP. This structural mimicry triggers the phosphorylation and activation of AMPK without altering overall cellular nucleotide ratios.
Academic and institutional laboratories study this mechanism across multiple experimental contexts:
Cellular Energy Regulation: Evaluates glucose uptake kinetics, fatty acid oxidation, and inhibition of hepatic gluconeogenesis in controlled in vitro models.
Signal Transduction Pathways: Assesses mitochondrial biogenesis markers, transcriptional coactivator expression, and metabolic stress responses.
Enzymatic Intermediates: Acts as a benchmark reference standard for investigating metabolic enzyme phosphorylation cascades.
When structuring in vitro assays, researchers evaluating an appropriate aicar peptide dosage must account for precise molar concentrations during reconstitution and cell culture media preparation. For academic facilities examining material expenditures, comparing the baseline aicar cost ensures long-term budgetary alignment across multi-phase experimental trials.
Investigators seeking a reliable resource to buy aicar must verify independent third-party analytical reports confirming high molecular purity and batch-to-batch consistency. Laboratories evaluating global suppliers or reviewing a certified aicar for sale listing should ensure materials are strictly designated for analytical testing, biochemical assays, and laboratory research rather than human consumption. Basepeptides.us maintains rigorous quality control protocols to support reproducible outcomes across all advanced scientific studies.
This product is sold strictly for laboratory research use only. Not for human consumption. By purchasing, you acknowledge that you are at least 18 years of age and that this product will be used exclusively for legitimate research purposes. Peptides require reconstitution, instructions are not provided, nor are directions on dosing and usage. Products are intended strictly for research purposes by skilled professionals.
