$49.99
At BasePeptides.us, we provide high-purity research compounds for advanced scientific investigations. Epithalon (also known as Epitalon) is a synthetic tetrapeptide consisting of the amino acid sequence Ala-Glu-Asp-Gly. Originally designed to mimic natural pineal-derived regulatory peptides, it has become a central focus in gerontological and cellular biology research due to its unique interactions with chromatin structure, telomerase activation, and neuroendocrine pathways.
Sequence: Ala-Glu-Asp-Gly (AEDG)
Molecular Weight: 390.35 g/mol
Purity: $\ge$99% (Verified via HPLC and Mass Spectrometry)
Form: Lyophilized reference powder
CAS Number: 307297-39-8
Storage: Store at -20°C, desiccated and protected from light
In vitro and preclinical laboratory models utilize the Epithalon peptide to investigate mechanisms associated with cellular senescence and genomic stability. Research indicates that the molecule interacts with linker histones and DNA promoter regions, which may facilitate chromatin remodeling and the de-repression of the human telomerase reverse transcriptase (hTERT) gene.
Key areas of experimental observation include:
Telomerase Activation: Evaluating enzymatic induction and its capacity to support telomere maintenance in somatic cell lines past standard replicative limits.
Oxidative Stress Resilience: Measuring endogenous antioxidant enzyme expression, including superoxide dismutase and catalase, under induced stress models.
Circadian Regulation: Assessing pineal-hypothalamic feedback loops and melatonin synthesis pathways in aging models.
When establishing experimental designs, investigators carefully calculate an appropriate epithalon dosage schedule based on in vitro viability thresholds or animal model parameters. Because reconstitution requires precise handling, protocol documentation often outlines standard epithalon dosing frequencies—typically administered in short cyclical intervals to evaluate cumulative cellular responses without inducing receptor desensitization.
For academic institutions and bio-analytical facilities evaluating project overhead, tracking transparent market metrics regarding an accessible epithalon for sale ensures consistent experimental budgeting. Sourcing reliable reference materials via BasePeptides.us guarantees third-party analytical verification, ensuring high-purity standards for all cellular and molecular research.
This product is sold strictly for laboratory research use only. Not for human consumption. By purchasing, you acknowledge that you are at least 18 years of age and that this product will be used exclusively for legitimate research purposes. Peptides require reconstitution, instructions are not provided, nor are directions on dosing and usage. Products are intended strictly for research purposes by skilled professionals.
