$89.99
At BasePeptides.us, we supply premium-grade research compounds for advanced laboratory investigations. LL-37 is a well-characterized, human cationic antimicrobial peptide (CAMP) derived from the carboxy-terminal end of the human cathelicidin antimicrobial protein (hCAP18). Comprising 37 amino acids, this amphipathic alpha-helical peptide serves as a critical component of the innate immune system, mediating direct host defense mechanisms, immunomodulatory pathways, and epithelial cell recruitment.
Molecular Weight: 4493.33 g/mol
Purity: $\ge$98% (HPLC and Mass Spectrometry Verified)
Form: Lyophilized reference powder
CAS Number: 154947-66-7
Storage: Store at -20°C, desiccated and protected from light
In vitro and preclinical studies focus on the unique structural properties of the ll-37 peptide and its interactions with biological membranes. Because of its amphipathic structure, the molecule adopts an alpha-helical conformation upon interacting with lipid bilayers, allowing it to modulate membrane permeability and influence cellular signaling cascades.
Academic laboratories evaluate several key areas when handling this compound:
Membrane Interaction Kinetics: Investigates electrostatic binding affinity toward negatively charged bacterial cell walls and mammalian lipid bilayers.
Immunomodulatory Signaling: Assesses chemotactic recruitment of immune cells, cytokine release modulation, and wound re-epithelialization pathways.
Biofilm Disruption: Measures structural degradation parameters in microbial biofilm models.
When structuring in vitro experimental protocols, bio-analytical researchers examine documented ll-37 peptide benefits across cellular models, including its role in tissue repair and host defense response mechanisms. For institutions evaluating material options, finding a reliable source to buy ll-37 requires verifying third-party high-performance liquid chromatography (HPLC) purity reports and mass spectral analysis to ensure precise molecular weight validation.
Facilities comparing global suppliers or tracking down a dependable ll-37 peptide for sale must ensure that materials are strictly designated for laboratory research, analytical testing, and cellular assays rather than clinical or human administration. Basepeptides.us provides comprehensive quality assurance to support reproducible outcomes across all advanced research projects.
This product is sold strictly for laboratory research use only. Not for human consumption. By purchasing, you acknowledge that you are at least 18 years of age and that this product will be used exclusively for legitimate research purposes. Peptides require reconstitution, instructions are not provided, nor are directions on dosing and usage. Products are intended strictly for research purposes by skilled professionals.
